Gut Botany is divided into eight sections. In "Court Theatre," Kuppers revisits courtroom performances following her sexual assault while drawing from the works of Perel and Bhanu Kapil. "Asylum" grew out of the Asylum Project performance experiments that Kuppers co-directed with dancer/poet Stephanie Heit. "Moon Botany" began as a collaboration with visual artist Sharon Siskin and offers a wheelchair user's view of insects, mushrooms, and horsetail ferns. Amber DiPetra notes that "this book is beautiful when it needs to be beautiful and it is edgy when it needs to be edgy and that is the sign of writing that matters."